SCHEMBL856866

SCHEMBL856866

CCC(=O)/C=C/c1ccc(OC)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 2/20 0.80
RAB9A P51151 2/20 0.69
NPC1 O15118 1/20 0.69
F3 P13726 3/20 0.68
THRB P10828 1/20 0.66
ATM Q13315 1/20 0.66
HDAC3 O15379 2/20 0.62
HDAC1 Q13547 2/20 0.62
HDAC2 Q92769 2/20 0.62
HDAC8 Q9BY41 2/20 0.62
HDAC6 Q9UBN7 2/20 0.62
TAS1R3 Q7RTX0 2/20 0.59
TAS1R1 Q7RTX1 2/20 0.59
MAOB P27338 2/20 0.59
BACE1 P56817 1/20 0.58
HDAC4 P56524 1/20 0.57
HDAC7 Q8WUI4 1/20 0.57
HDAC10 Q969S8 1/20 0.57
HDAC11 Q96DB2 1/20 0.57
HDAC9 Q9UKV0 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL856867 1.00 GSK3B (0.80) GSK3BRAB9ANPC1F3THRB
SCHEMBL3440658 0.89 GSK3B (1.00) GSK3BRAB9ANPC1F3THRB
SCHEMBL3440661 0.89 GSK3B (1.00) GSK3BRAB9ANPC1F3THRB
SCHEMBL25853463 0.87 GSK3B (0.61) GSK3BRAB9ANPC1F3THRB
SCHEMBL20273237 0.86 GSK3B (0.75) GSK3BRAB9ANPC1F3THRB
SCHEMBL31289356 0.84 GSK3B (0.77) GSK3BRAB9ANPC1F3THRB
SCHEMBL30472941 0.84 GSK3B (0.77) GSK3BRAB9ANPC1F3THRB
SCHEMBL29047403 0.84 GSK3B (0.77) GSK3BRAB9ANPC1F3THRB
SCHEMBL25123555 0.83 GSK3B (0.75) GSK3BRAB9ANPC1F3THRB
SCHEMBL10348539 0.83 GSK3B (0.87) GSK3BRAB9ANPC1F3THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250212873-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-03 US claimed
US-20240306688-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2024-09-19 US claimed
CN-117897055-A Method for reducing abnormal odor 奇华顿股份有限公司 2024-04-16 CN claimed
US-20230148641-A1 FLAVOR COMPOSITION FIRMENICH SA (CH) 2023-05-18 US claimed
CN-111175411-B Method for determining sensitized aromatics in water color pens and fluorescent pens by microwave-assisted extraction-gas chromatography-mass spectrometry 山东省产品质量检验研究院 2020-09-22 CN claimed
EP-3649183-A1 SILICONE COMPOUNDS The Procter and Gamble Company (US) 2020-05-13 EP claimed
WO-2019010263-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2019-01-10 WO claimed
US-20190010293-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2019-01-10 US claimed
US-20190010427-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2019-01-10 US claimed
US-20090004360-A1 Taste Potentiator Compositions in Oral Delivery Systems CADBURY ADAMS USA LLC (US) 2009-01-01 US claimed
US-20250212873-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-03 US disclosed
US-20240306688-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2024-09-19 US disclosed
US-20240277012-A1 DUPLICATE BEVERAGE WANG JIE (US) 2024-08-22 US disclosed
EP-3845887-B1 SKIN SENSITIZATION MEASURING METHOD FUJIFILM CORP (JP) 2024-05-01 EP disclosed
CN-117897055-A Method for reducing abnormal odor 奇华顿股份有限公司 2024-04-16 CN disclosed
US-4766249-A Method of catalytically hydrolyzing alpha, beta-unsaturated carbonyl compounds MALLINCKRODT, INC. (US) 1988-08-23 US disclosed
CN-88100615-A The hydrolytic action of active ketene and olefine aldehydr 1988-08-17 CN disclosed
US-4709098-A Hydrolysis of activated olefinic ketones and aldehydes MALLINCKRODT, INC. (US) 1987-11-24 US disclosed
EP-0242934-A2 Method of catalytically hydrolyzing alpha,beta-unsaturated carbonyl compounds FRIES & FRIES, INC. (US) 1987-10-28 EP disclosed
US-3978240-A FLAVORING LEVER BROTHERS COMPANY (US) 1976-08-31 US disclosed