Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925822 | 0.89 | DPP4 (0.51) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9079097 | 0.89 | DPP4 (0.51) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL8925290 | 0.89 | DPP4 (0.51) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL8925416 | 0.89 | DPP4 (0.51) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9457172 | 0.89 | DPP4 (0.51) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL8567141 | 0.87 | KMT2A (0.62) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL8567576 | 0.85 | KCNH2 (0.59) | CHRM2LMNAKDM4EHSD17B10KCNH2 | |
| SCHEMBL8565924 | 0.85 | KDM4E (0.60) | LMNAKDM4EHSD17B10KCNH2CYP2C9 | |
| SCHEMBL16213290 | 0.84 | DPP4 (0.52) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL10389874 | 0.84 | DPP4 (0.54) | DPP4CHRM2DRD1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559752-B1 | OPTICAL ISOMERS OF 7- 3-(1,1-DIALKYLMETHYL-1-AMINO-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 1998-01-28 | — | — | EP | disclosed |
| US-5364861-A | Bactericides with side effect reduction | WARNER-LAMBERT COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| US-5278317-A | Aminomethylpyrrole | WARNER-LAMBERT COMPANY (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0559752-A1 | OPTICAL ISOMERS OF 7- 3-(1,1-DIALKYLMETHYL-1-AMINO-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5157128-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1992-10-20 | — | — | US | disclosed |
| WO-1992009597-A1 | OPTICAL ISOMERS OF 7-[3-(1,1-DIALKYLMETHYL-1-AMINO-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1992-06-11 | — | — | WO | disclosed |
| US-5072001-A | Bactericides | WARNER-LAMBERT COMPANY (US) | 1991-12-10 | — | — | US | disclosed |