SCHEMBL8568699

SCHEMBL8568699

Nc1cnc(Br)cc1N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30547261 0.81
SCHEMBL29331921 0.81 HTT (0.36)
SCHEMBL4828045 0.81
SCHEMBL10184778 0.81
SCHEMBL1600771 0.79
SCHEMBL23461735 0.77
SCHEMBL2596826 0.77
SCHEMBL31125230 0.77
SCHEMBL17901852 0.77
SCHEMBL21246871 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102558041-A Method for preparing 3,4-diamino-6-bromopyridine HEFEI COSCIENCE MEDICINE TECHNOLOGY CO LTD 2012-07-11 CN claimed
WO-2026102082-A1 ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-14 US disclosed
EP-4676926-A1 BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS ThirtyFiveBio Limited (GB) 2026-01-14 EP disclosed
US-20250333399-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES KHORA SPV 1 LLC (US) 2025-10-30 US disclosed
US-12331039-B2 Inhibitors of fibroblast growth factor receptor kinases KHORA SPV 1, LLC (US) 2025-06-17 US disclosed
EP-4559908-A1 HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF S2CBio Inc. (KR) 2025-05-28 EP disclosed
WO-2025099451-A1 NEW COMPOUNDS AND METHODS Transition Bio Limited (GB) 2025-05-15 WO disclosed
WO-2024184650-A1 BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS. ThirtyFiveBio Limited (GB) 2024-09-12 WO disclosed
EP-3567041-B1 SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF IMPACT THERAPEUTICS SHANGHAI INC (CN) 2023-12-27 EP disclosed
WO-2013048214-A2 NOVEL HETEROCYCLIC DERIVATIVES AND THEIR USES C&C RESEARCH LABORATORIES (KR) 2013-04-04 WO disclosed
CN-202376959-U Liquid ammonia preparation device applied to production of 3,4-diamido-6-bromopyridine HEFEI KESHANG MEDICAL TECHNOLOGY CO LTD 2012-08-15 CN disclosed
CN-202376959-U Liquid ammonia preparation device applied to production of 3,4-diamido-6-bromopyridine HEFEI KESHANG MEDICAL TECHNOLOGY CO LTD 2012-08-15 CN disclosed
CN-102558041-A Method for preparing 3,4-diamino-6-bromopyridine HEFEI COSCIENCE MEDICINE TECHNOLOGY CO LTD 2012-07-11 CN disclosed
CN-102558041-A Method for preparing 3,4-diamino-6-bromopyridine HEFEI COSCIENCE MEDICINE TECHNOLOGY CO LTD 2012-07-11 CN disclosed
CN-102558041-A Method for preparing 3,4-diamino-6-bromopyridine HEFEI COSCIENCE MEDICINE TECHNOLOGY CO LTD 2012-07-11 CN disclosed
WO-2011149856-A1 INHIBITORS OF HCV NS5A PRESIDIO PHARMACEUTICALS, INC. (US) 2011-12-01 WO disclosed
US-5795889-A INHIBITING CELL GROWTH WITH ENZYME INHIBITORS FOR SKIN DISORDERS RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-08-18 US disclosed
US-5646153-A INHIBITING ABNORMAL CELL PROLIFERATION RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1997-07-08 US disclosed
US-5480883-A Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1996-01-02 US disclosed