Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568764 | 1.00 | PARP1 (0.50) | PARP1HTTALDH1A1POLBGAA | |
| SCHEMBL15047755 | 0.86 | ATM (0.37) | PARP1HTTALDH1A1POLBGAA | |
| SCHEMBL2091649 | 0.78 | PARP1 (0.50) | PARP1HTTALDH1A1POLBGAA | |
| SCHEMBL13335454 | 0.78 | HTT (0.50) | PARP1HTTALDH1A1POLBGAA | |
| SCHEMBL28365847 | 0.78 | HTT (0.50) | PARP1HTTALDH1A1POLBGAA | |
| SCHEMBL24710340 | 0.78 | HTT (0.50) | PARP1HTTALDH1A1POLBGAA | |
| SCHEMBL29952754 | 0.78 | PARP1 (0.50) | PARP1HTTALDH1A1POLBGAA | |
| SCHEMBL7396746 | 0.77 | PARP1 (0.48) | PARP1HTTALDH1A1POLBGAA | |
| SCHEMBL7477836 | 0.76 | PARP1 (0.44) | PARP1HTTALDH1A1POLBGAA | |
| SCHEMBL10599512 | 0.76 | PARP1 (0.44) | PARP1HTTALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643781-B1 | ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS | SEPRACOR INC (US) | 1998-06-24 | — | — | EP | claimed |
| US-5419817-A | Osmium tetroxide catalyst; preparing hydroxycarbonyl compounds from enol ether or vinyl halide | SEPRACOR INC. (US) | 1995-05-30 | — | — | US | claimed |
| EP-0643781-A1 | ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS | SEPRACOR, INC. (US) | 1995-03-22 | — | — | EP | claimed |
| WO-1993017150-A1 | ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS | SEPRACOR, INC. (US) | 1993-09-02 | — | — | WO | claimed |
| EP-0643781-B1 | ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS | SEPRACOR INC (US) | 1998-06-24 | — | — | EP | disclosed |
| US-5419817-A | Osmium tetroxide catalyst; preparing hydroxycarbonyl compounds from enol ether or vinyl halide | SEPRACOR INC. (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0643781-A4 | ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS. | — | 1995-04-26 | — | — | EP | disclosed |
| EP-0643781-A1 | ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS | SEPRACOR, INC. (US) | 1995-03-22 | — | — | EP | disclosed |
| US-5302257-A | Preparing optically active glycols using catalyst complex of osmium tetroxide and chiral oxidation resistant tertiary amine, employing secondary oxidant to generate osmium tetroxide, electrolytically regenerating secondary oxidant | SEPRACOR, INC. (US) | 1994-04-12 | — | — | US | disclosed |
| WO-1993017150-A1 | ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS | SEPRACOR, INC. (US) | 1993-09-02 | — | — | WO | disclosed |