Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568862 | 1.00 | NR1H2 (0.39) | NR1H2SRCMEN1KMT2AALDH1A1 | |
| SCHEMBL17930974 | 0.81 | NR1H2 (0.41) | NR1H2SRCMEN1KMT2AALDH1A1 | |
| SCHEMBL142689 | 0.80 | NR1H2 (0.42) | NR1H2SRCMEN1KMT2AALDH1A1 | |
| SCHEMBL139880 | 0.80 | NR1H2 (0.42) | NR1H2SRCMEN1KMT2AALDH1A1 | |
| SCHEMBL1241324 | 0.80 | NR1H2 (0.42) | NR1H2SRCMEN1KMT2AALDH1A1 | |
| SCHEMBL20312947 | 0.80 | NR1H2 (0.42) | NR1H2SRCMEN1KMT2AALDH1A1 | |
| SCHEMBL19964151 | 0.80 | NR1H2 (0.42) | NR1H2SRCMEN1KMT2AALDH1A1 | |
| SCHEMBL1372634 | 0.80 | NR1H2 (0.42) | NR1H2SRCMEN1KMT2AALDH1A1 | |
| SCHEMBL21286125 | 0.80 | NR1H2 (0.42) | NR1H2SRCMEN1KMT2AALDH1A1 | |
| SCHEMBL1241323 | 0.80 | NR1H2 (0.42) | NR1H2SRCMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |