SCHEMBL8568936

SCHEMBL8568936

FC(F)(F)COC1CCCO1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
KDM4C Q9H3R0 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8572408 0.94 MEN1 (0.37) TACR1MEN1KMT2AL3MBTL1KDM4C
SCHEMBL8568789 0.83 MEN1 (0.31) MEN1KMT2AL3MBTL1KDM4C
SCHEMBL14961344 0.80
SCHEMBL13923773 0.80 MEN1 (0.32) MEN1KMT2A
SCHEMBL23448987 0.80 MEN1 (0.33) MEN1KMT2AL3MBTL1KDM4C
SCHEMBL14961269 0.79 MEN1 (0.36) MEN1KMT2AL3MBTL1KDM4C
SCHEMBL14961379 0.79
SCHEMBL8568200 0.78 MEN1 (0.35) MEN1KMT2AKDM4C
SCHEMBL8570171 0.78 MEN1 (0.35) MEN1KMT2AL3MBTL1KDM4C
SCHEMBL12809618 0.78 MEN1 (0.38) MEN1KMT2AL3MBTL1KDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744678-A NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY NIPPON OIL CO., LTD. (JP) 1998-04-28 US disclosed
US-5728641-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1998-03-17 US disclosed
EP-0758563-A1 OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT NIPPON OIL COMPANY, LTD. (JP) 1997-02-19 EP disclosed
EP-0587440-A2 Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same NIPPON OIL COMPANY, LIMITED (JP) 1994-03-16 EP disclosed