Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 4/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747738 | 0.79 | TOP2A (0.39) | KDM4ESMN1; SMN2CYP1A2KMT2ATOP2A | |
| SCHEMBL8568882 | 0.73 | KDM4E (0.57) | KDM4ETOP2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL8576863 | 0.73 | KDM4E (0.57) | KDM4ETOP2AALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL8570439 | 0.73 | KDM4E (0.56) | KDM4ETOP2AALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9074218 | 0.73 | KDM4E (0.45) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL9073984 | 0.73 | KDM4E (0.45) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL1289900 | 0.72 | NOTUM (0.39) | KDM4ESMN1; SMN2CYP1A2TOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL8563725 | 0.71 | NOTUM (0.38) | KDM4ESMN1; SMN2CYP1A2TOP2ATOP2B | |
| SCHEMBL8574268 | 0.71 | TOP2A (0.45) | KDM4ETOP2ATOP2BALDH1A1HPGD | |
| SCHEMBL8565469 | 0.71 | TOP2A (0.45) | KDM4ETOP2ATOP2BALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |