Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15150627 | 0.84 | CYP1A2 (0.50) | TSHRCYP1A2POLBALDH1A1MEN1 | |
| SCHEMBL8570123 | 0.82 | CYP1A2 (0.48) | TSHRCYP1A2POLBALDH1A1MEN1 | |
| SCHEMBL4826614 | 0.81 | CYP1A2 (0.47) | TSHRCYP1A2POLBALDH1A1MEN1 | |
| SCHEMBL8603033 | 0.81 | CYP1A2 (0.47) | TSHRCYP1A2POLBALDH1A1MEN1 | |
| SCHEMBL29381779 | 0.79 | POLB (0.51) | TSHRCYP1A2POLBALDH1A1MEN1 | |
| SCHEMBL202663 | 0.79 | POLB (0.51) | TSHRCYP1A2POLBALDH1A1MEN1 | |
| SCHEMBL15923536 | 0.79 | CYP1A2 (0.45) | TSHRCYP1A2POLBALDH1A1MEN1 | |
| SCHEMBL8560017 | 0.79 | CYP1A2 (0.51) | TSHRCYP1A2POLBALDH1A1MEN1 | |
| SCHEMBL8599650 | 0.79 | CYP1A2 (0.51) | TSHRCYP1A2POLBALDH1A1MEN1 | |
| SCHEMBL13645413 | 0.78 | MAPT (0.46) | TSHRCYP1A2POLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |