Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 3/20 | 0.60 |
| ▸ | WNT3A | P56704 | 3/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 9/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2900730 | 0.83 | CTNNB1 (0.59) | CTNNB1WNT3AHDAC3HDAC4HDAC1 | |
| SCHEMBL15980096 | 0.79 | CTNNB1 (0.62) | CTNNB1WNT3AHDAC3HDAC4HDAC1 | |
| SCHEMBL15968487 | 0.78 | CTNNB1 (0.74) | CTNNB1WNT3AHDAC3HDAC4HDAC1 | |
| SCHEMBL28753366 | 0.77 | HDAC3 (0.63) | CTNNB1WNT3AHDAC3HDAC4HDAC1 | |
| SCHEMBL639330 | 0.77 | CTNNB1 (0.59) | CTNNB1WNT3AHDAC3HDAC4HDAC1 | |
| SCHEMBL15980090 | 0.77 | CTNNB1 (0.70) | CTNNB1WNT3AHDAC3HDAC4HDAC1 | |
| SCHEMBL15979966 | 0.77 | CTNNB1 (0.68) | CTNNB1WNT3AHDAC3HDAC4HDAC1 | |
| SCHEMBL15979916 | 0.76 | CTNNB1 (0.60) | CTNNB1WNT3AHDAC3HDAC4HDAC1 | |
| SCHEMBL15979978 | 0.75 | CTNNB1 (0.77) | CTNNB1WNT3AHDAC3HDAC4HDAC1 | |
| SCHEMBL15980091 | 0.75 | CTNNB1 (0.67) | CTNNB1WNT3AHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739336-A | SELECTIVE 5-HYDROXYTRYPTAMINE-2C RECEPTOR ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1998-04-14 | — | — | US | disclosed |
| WO-1997000872-A1 | 1,3,8-TRIAZA- AND 3,8-DIAZA-1-OXASPIRO(4,5)DECANE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 1997-01-09 | — | — | WO | disclosed |