SCHEMBL8569442

SCHEMBL8569442

CCCCCCCC=Cc1ccc(-c2ncc(CCCCCC(C)F)cn2)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.35
ASAH2 Q9NR71 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PPARA Q07869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8667524 1.00 RARB (0.35) RARBASAH2KDM4EMEN1USP2
SCHEMBL7510141 0.92 RARB (0.41) RARBASAH2KDM4EMEN1USP2
SCHEMBL7509223 0.92 RARB (0.41) RARBASAH2KDM4EMEN1USP2
SCHEMBL7511707 0.92 RARB (0.41) RARBASAH2KDM4EMEN1USP2
SCHEMBL7513414 0.92 RARB (0.41) RARBASAH2KDM4EMEN1USP2
SCHEMBL7511695 0.92 RARB (0.41) RARBASAH2KDM4EMEN1USP2
SCHEMBL7509214 0.92 RARB (0.41) RARBASAH2KDM4EMEN1USP2
SCHEMBL7510133 0.92 RARB (0.41) RARBASAH2KDM4EMEN1USP2
SCHEMBL7513419 0.92 RARB (0.41) RARBASAH2KDM4EMEN1USP2
SCHEMBL8665778 0.91 RARB (0.37) RARBASAH2KDM4EMEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0667384-B1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL CO (JP) 1998-12-16 EP disclosed
US-5779934-A FLUORINATING AN ALCOHOL DERIVATIVE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-07-14 US disclosed
EP-0667384-A1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-08-16 EP disclosed