Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 11/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5465872 | 0.85 | PTGER1 (0.57) | PTGER1KMT2ALRRK2CYP2C9MRGPRX4 | |
| SCHEMBL5627922 | 0.82 | PTGER1 (0.55) | PTGER1KMT2ALRRK2CYP2C9MRGPRX4 | |
| SCHEMBL487486 | 0.82 | PTGER1 (0.75) | PTGER1KMT2ALRRK2CYP2C9MRGPRX4 | |
| SCHEMBL21494209 | 0.82 | LRRK2 (0.52) | PTGER1KMT2ALRRK2MRGPRX4FOLH1 | |
| SCHEMBL8574076 | 0.81 | TSHR (0.45) | KMT2A | |
| SCHEMBL5460706 | 0.81 | PTGER1 (0.65) | PTGER1KMT2ALRRK2CYP2C9MRGPRX4 | |
| SCHEMBL5464691 | 0.80 | PTGER1 (0.52) | PTGER1KMT2ALRRK2CYP2C9 | |
| SCHEMBL4722050 | 0.80 | PTGER1 (0.64) | PTGER1KMT2ALRRK2CYP2C9MRGPRX4 | |
| SCHEMBL3729989 | 0.80 | PTGER1 (0.64) | PTGER1KMT2ALRRK2CYP2C9MRGPRX4 | |
| SCHEMBL29836110 | 0.80 | PTGER1 (0.64) | PTGER1KMT2ALRRK2CYP2C9MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739336-A | SELECTIVE 5-HYDROXYTRYPTAMINE-2C RECEPTOR ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1998-04-14 | — | — | US | disclosed |
| WO-1997000872-A1 | 1,3,8-TRIAZA- AND 3,8-DIAZA-1-OXASPIRO(4,5)DECANE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 1997-01-09 | — | — | WO | disclosed |