Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.40 |
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20099912 | 0.98 | UHRF1 (0.42) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL8565055 | 0.93 | UHRF1 (0.43) | UHRF1CCR1CCR5CCR8KDM4E | |
| Bromide SCHEMBL38664578 | 0.89 | UHRF1 (0.41) | UHRF1CCR1CCR5CCR8KDM4E | |
| Hydrochloric Acid SCHEMBL10858865 | 0.87 | UHRF1 (0.48) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL6466772 | 0.85 | UHRF1 (0.46) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL2547957 | 0.84 | KCNH2 (0.48) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL28878273 | 0.84 | KCNH2 (0.48) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL28183218 | 0.84 | KCNH2 (0.48) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL8569698 | 0.84 | UHRF1 (0.42) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL2551597 | 0.84 | KCNH2 (0.48) | UHRF1CCR1CCR5CCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315492-B1 | PYRAZOLE DERIVATIVE, OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | KISSEI PHARMACEUTICAL (JP) | 2020-09-16 | — | — | EP | disclosed |
| EP-0824524-A1 | ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE | PHARMACIA & UPJOHN COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |