Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.53 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.53 |
| ▸ | BCL6 | P41182 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487452 | 0.86 | EGFR (0.65) | EGFRERBB2ERBB4BCL6MAPT | |
| SCHEMBL6998926 | 0.79 | EGFR (0.67) | EGFRERBB2ERBB4BCL6MAPT | |
| SCHEMBL4353234 | 0.76 | EGFR (0.70) | EGFRERBB2ERBB4BCL6MAPT | |
| SCHEMBL8488091 | 0.76 | EGFR (0.67) | EGFRERBB2ERBB4BCL6MAPT | |
| SCHEMBL8487730 | 0.76 | EGFR (0.67) | EGFRERBB2BCL6MAPTHPGD | |
| SCHEMBL6989314 | 0.74 | EGFR (0.70) | EGFRERBB2MAPTGRM1HPGD | |
| SCHEMBL6998946 | 0.74 | EGFR (0.70) | EGFRERBB2BCL6MAPTHPGD | |
| SCHEMBL6997252 | 0.74 | EGFR (0.69) | EGFRERBB2ERBB4MAPTGRM1 | |
| SCHEMBL8488839 | 0.73 | EGFR (0.73) | EGFRERBB2ERBB4BCL6MAPT | |
| SCHEMBL8488112 | 0.73 | EGFR (0.73) | EGFRERBB2ERBB4BCL6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885226-A1 | 4-AMINO PYRIMIDINE DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PRODUCTION | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997032881-A1 | 4-AMINO PYRIMIDINE DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PRODUCTION | DR. KARL THOMAE GMBH (DE) | 1997-09-12 | — | — | WO | disclosed |