Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.46 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 3/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554187 | 0.90 | DHODH (0.50) | NPC1PKN1PKN2MKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL8570223 | 0.89 | DHODH (0.49) | NPC1PKN1PKN2MKNK1MKNK2 | |
| SCHEMBL1553002 | 0.89 | NPC1 (0.48) | NPC1PKN1PKN2MKNK1MKNK2 | |
| SCHEMBL8653067 | 0.87 | TNKS (0.51) | GSK3BDHODHPARP1PARP2HPSE | |
| SCHEMBL1553232 | 0.83 | PDE4D (0.59) | — | |
| SCHEMBL8603042 | 0.81 | PDE4A (0.48) | NPC1MKNK1MKNK2ALDH1A1DHODH | |
| SCHEMBL8571233 | 0.80 | NPC1 (0.46) | NPC1PKN1PKN2MKNK1MKNK2 | |
| SCHEMBL4702865 | 0.78 | NPC1 (0.72) | NPC1MKNK1MKNK2ALDH1A1CYP11B1 | |
| SCHEMBL1553486 | 0.77 | DHODH (0.57) | ALDH1A1GSK3BDHODHPARP1PARP2 | |
| Hydrochloric Acid SCHEMBL8653073 | 0.76 | DHODH (0.56) | ALDH1A1GSK3BDHODHPARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |