Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564044 | 1.00 | MEN1 (0.42) | MEN1KMT2AGPR35TDP1L3MBTL1 | |
| SCHEMBL7220671 | 0.91 | NR4A1 (0.41) | MEN1KMT2AGPR35TDP1L3MBTL1 | |
| SCHEMBL13070165 | 0.83 | SMN1; SMN2 (0.41) | MEN1KMT2AGPR35TDP1L3MBTL1 | |
| SCHEMBL13350187 | 0.81 | SMN1; SMN2 (0.40) | MEN1KMT2AGPR35TDP1L3MBTL1 | |
| SCHEMBL13299590 | 0.81 | SMN1; SMN2 (0.40) | MEN1KMT2AGPR35TDP1L3MBTL1 | |
| SCHEMBL18339812 | 0.81 | KMT2A (0.45) | MEN1KMT2AGPR35TDP1SMN1; SMN2 | |
| SCHEMBL8516525 | 0.80 | KMT2A (0.56) | MEN1KMT2ATDP1L3MBTL1KDM4E | |
| SCHEMBL13010111 | 0.79 | SMN1; SMN2 (0.38) | MEN1KMT2AGPR35TDP1SMN1; SMN2 | |
| SCHEMBL2215346 | 0.78 | MAPT (0.41) | MEN1KMT2AGPR35TDP1SMN1; SMN2 | |
| SCHEMBL5333511 | 0.78 | MAPT (0.41) | MEN1KMT2AGPR35TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750567-A | TETRAHYDRONAPHTHYL DERIVATIVES | PHONE-POULENC RORER SA. (FR) | 1998-05-12 | — | — | US | disclosed |