⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL387955 | 0.96 | — | — | |
| SCHEMBL4589963 | 0.78 | — | — | |
| SCHEMBL12458655 | 0.75 | — | — | |
| SCHEMBL2356514 | 0.73 | — | — | |
| SCHEMBL16572868 | 0.72 | — | — | |
| SCHEMBL27880873 | 0.70 | — | — | |
| Methane SCHEMBL1527049 | 0.70 | — | — | |
| SCHEMBL51798 | 0.67 | — | — | |
| SCHEMBL339997 | 0.67 | — | — | |
| SCHEMBL11406606 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5759529-A | Silicone composition for skin care | DOW CORNING CORPORATION (US) | 1998-06-02 | — | — | US | disclosed |
| US-5750098-A | Silicone compositions for skin care | DOW CORNING CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |
| US-5679335-A | APPLYING TO DECREASE TRANSEPIDERMAL WATER LOSS | DOW CORNING CORPORATION (US) | 1997-10-21 | — | — | US | disclosed |
| EP-0610014-B1 | Silicone compositions for skin care | DOW CORNING (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5512694-A | Addition-curable silicone adhesive compositions and bis(trialkoxysilyl) alpha-amino ester adhesion promoters | GENERAL ELECTRIC COMPANY (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0566240-B1 | Alkylmethylsiloxane containing perfume compositions | DOW CORNING (US) | 1996-04-10 | — | — | EP | disclosed |
| US-5475044-A | Hydrosilation catalyst, fillers; bonding plastic and metal substrates | GENERAL ELECTRIC COMPANY (US) | 1995-12-12 | — | — | US | disclosed |
| EP-0657157-A1 | Styling aid containing a volatile alkylmethylsilicone | DOW CORNING CORPORATION (US) | 1995-06-14 | — | — | EP | disclosed |
| EP-0610014-A1 | Silicone compositions for skin care | DOW CORNING CORPORATION (US) | 1994-08-10 | — | — | EP | disclosed |
| EP-0566240-A1 | Alkylmethylsiloxane containing perfume compositions | DOW CORNING CORPORATION (US) | 1993-10-20 | — | — | EP | disclosed |
| EP-0531001-A1 | Cyclic alkylmethylsiloxanes for skin care | DOW CORNING CORPORATION (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5160494-A | Alkylmethylsiloxane containing perfume compositions | DOW CORNING CORPORATION (US) | 1992-11-03 | — | — | US | disclosed |