Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.58 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8087177 | 0.99 | GRIN1 (0.57) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8568020 | 0.90 | GRIN1 (0.58) | GRIN1 | |
| Bromide SCHEMBL8091961 | 0.89 | GRIN1 (0.57) | GRIN1 | |
| SCHEMBL8562825 | 0.83 | GRIN1 (0.55) | GRIN1 | |
| Bromide SCHEMBL8092139 | 0.82 | GRIN1 (0.54) | GRIN1 | |
| SCHEMBL8500329 | 0.81 | GRIN1 (0.54) | GRIN1 | |
| SCHEMBL8566608 | 0.81 | GRIN1 (0.53) | GRIN1 | |
| SCHEMBL8500903 | 0.81 | GRIN1 (0.53) | GRIN1 | |
| Hydrochloric Acid SCHEMBL8564723 | 0.80 | GRIN1 (0.53) | GRIN1 | |
| SCHEMBL5973748 | 0.80 | GRIN1 (0.65) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853617-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | Novartis AG (CH) | 1998-07-22 | — | — | EP | claimed |
| WO-1997008155-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | claimed |