Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | GSK3B | P49841 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18383362 | 0.85 | EGLN1 (0.83) | EGLN1HIF1AKDM4EGSK3BMEN1 | |
| SCHEMBL8244419 | 0.85 | EGLN1 (1.00) | EGLN1HIF1AKDM4EGSK3BMEN1 | |
| SCHEMBL5330412 | 0.83 | EGLN1 (0.83) | EGLN1HIF1AKDM4EGSK3BMEN1 | |
| SCHEMBL1440727 | 0.83 | EGLN1 (0.67) | EGLN1HIF1AKDM4EGSK3BMEN1 | |
| SCHEMBL19434051 | 0.81 | HIF1A (0.77) | EGLN1HIF1AKDM4EGSK3BMEN1 | |
| SCHEMBL24054656 | 0.80 | HIF1A (0.72) | EGLN1HIF1AKDM4EGSK3BMEN1 | |
| SCHEMBL16522300 | 0.80 | GSK3B (0.79) | EGLN1HIF1AKDM4EGSK3BMEN1 | |
| SCHEMBL24054539 | 0.80 | MEN1 (0.72) | EGLN1HIF1AKDM4EGSK3BMEN1 | |
| SCHEMBL24054669 | 0.80 | MEN1 (0.74) | EGLN1HIF1AKDM4EGSK3BMEN1 | |
| SCHEMBL1522936 | 0.80 | KDM4E (0.81) | EGLN1HIF1AKDM4EGSK3BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066478-A1 | QUINOLINONE DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-05-24 | — | — | WO | disclosed |