Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | PDE4A | P27815 | 4/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572687 | 0.92 | PDE4A (0.44) | SMN1; SMN2GAAPDE4APDE4BPDE4C | |
| SCHEMBL1553076 | 0.91 | KDM4A (0.46) | SMN1; SMN2GAAPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL8570996 | 0.90 | KDM4A (0.45) | SMN1; SMN2GAAPDE4APDE4BPDE4C | |
| SCHEMBL8568575 | 0.90 | SMN1; SMN2 (0.49) | SMN1; SMN2GAAPDE4APDE4BPDE4C | |
| SCHEMBL1554630 | 0.89 | GAA (0.46) | SMN1; SMN2GAAPDE4APDE4BPDE4C | |
| SCHEMBL8571856 | 0.86 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL8575066 | 0.84 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL1552948 | 0.84 | KDM5A (0.51) | SMN1; SMN2GAAPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL8572692 | 0.83 | KDM5A (0.50) | SMN1; SMN2GAAPDE4APDE4BPDE4C | |
| SCHEMBL8571347 | 0.83 | PDE4D (0.59) | PDE4APDE4BPDE4CPDE4DRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |