⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719140 | 0.55 | — | — | |
| SCHEMBL3092227 | 0.53 | — | — | |
| SCHEMBL10758404 | 0.46 | — | — | |
| SCHEMBL29525891 | 0.41 | KDM4E (0.40) | — | |
| SCHEMBL29525411 | 0.41 | KDM4E (0.40) | — | |
| Water SCHEMBL6346266 | 0.37 | KDM4E (0.46) | — | |
| Water SCHEMBL1813560 | 0.37 | KDM4E (0.46) | — | |
| SCHEMBL23462230 | 0.30 | — | — | |
| SCHEMBL23462133 | 0.30 | — | — | |
| SCHEMBL23462036 | 0.30 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252745-A | Preparation and use of iodopropargyl esters of α-amino acid derivatives as antimicrobial agents | ROHM AND HAAS COMPANY (US) | 1993-10-12 | — | — | US | claimed |
| JP-10104778-A | — | — | None | — | — | JP | disclosed |
| US-5753649-A | Therapeutic agent for osteoporosis and diazepine compound | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| JP-H10104778-A | SILVER HALIDE PHOTOGRAPHIC SENSITIVE MATERIAL | KONICA CORP | 1998-04-24 | — | — | JP | disclosed |
| US-5593988-A | DIAZIPINE DERIVATIVES OF THIOPHENE FOR BONE DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| WO-1996023543-A1 | PHOTOLYTIC DRUG DELIVERY SYSTEMS | ANGIOMEDICS II INCORPORATED (US) | 1996-08-08 | — | — | WO | disclosed |
| EP-0638560-A1 | REMEDY FOR OSTEOPOROSIS AND DIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| EP-0342587-B1 | Thienotriazolodiazepine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1994-11-17 | — | — | EP | disclosed |
| US-5252745-A | Preparation and use of iodopropargyl esters of α-amino acid derivatives as antimicrobial agents | ROHM AND HAAS COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0315698-B1 | THIENO(TRIAZOLO)DIAZEPINE COMPOUNDS AND MEDICINAL APPLICATION OF THE SAME | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-4960770-A | Vasodilating agents, cardiovascular disorder | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| US-4910194-A | Structure substituted with phenyl group | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0342587-A2 | Thienotriazolodiazepine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-11-23 | — | — | EP | disclosed |