Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.71 |
| ▸ | PDE4A | P27815 | 19/20 | 0.71 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571283 | 0.83 | PDE4A (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8570083 | 0.82 | PDE4A (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8569960 | 0.82 | PDE4A (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8571835 | 0.74 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7321654 | 0.73 | PDE4A (0.82) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13526162 | 0.73 | PDE4B (0.73) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7401328 | 0.73 | PDE4A (0.55) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6585249 | 0.72 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6584436 | 0.72 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL5495203 | 0.72 | PDE4A (1.00) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |