Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574282 | 1.00 | KCNH2 (0.49) | KCNH2SCN5AALDH1A1KDM4EHPGD | |
| SCHEMBL8574272 | 1.00 | KCNH2 (0.49) | KCNH2SCN5AALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL7504231 | 0.99 | KCNH2 (0.48) | KCNH2SCN5AALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL7504223 | 0.99 | KCNH2 (0.48) | KCNH2SCN5AALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL7504219 | 0.99 | KCNH2 (0.48) | KCNH2SCN5AALDH1A1KDM4EHPGD | |
| SCHEMBL8576032 | 0.93 | KCNH2 (0.49) | KCNH2SCN5AALDH1A1KDM4EHPGD | |
| SCHEMBL8567918 | 0.93 | KCNH2 (0.49) | KCNH2SCN5AALDH1A1KDM4EHPGD | |
| SCHEMBL8576029 | 0.93 | KCNH2 (0.49) | KCNH2SCN5AALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL7495052 | 0.92 | KCNH2 (0.48) | KCNH2SCN5AALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL7495060 | 0.92 | KCNH2 (0.48) | KCNH2SCN5AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | claimed |
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |