Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | PTGFR | P43088 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5893724 | 0.85 | EGFR (0.64) | EIF2AK2CSNK2A2CSNK2BCSNK2A1EGFR | |
| SCHEMBL5893730 | 0.85 | EGFR (0.64) | EIF2AK2CSNK2A2CSNK2BCSNK2A1EGFR | |
| SCHEMBL3685249 | 0.83 | EGFR (0.53) | EIF2AK2CSNK2A2CSNK2BCSNK2A1EGFR | |
| SCHEMBL3685251 | 0.83 | EGFR (0.53) | EIF2AK2CSNK2A2CSNK2BCSNK2A1EGFR | |
| SCHEMBL9613260 | 0.82 | ESR1 (0.55) | EGFRPTGS2SMN1; SMN2AKR1C3MIF | |
| SCHEMBL9390825 | 0.81 | PTGER3 (0.52) | EGFRPTGS2SMN1; SMN2MIFALDH1A1 | |
| SCHEMBL26186761 | 0.78 | EIF2AK2 (0.51) | EIF2AK2CSNK2A2CSNK2BCSNK2A1SMN1; SMN2 | |
| SCHEMBL5448079 | 0.78 | EIF2AK2 (0.55) | EIF2AK2CSNK2A2CSNK2BCSNK2A1EGFR | |
| SCHEMBL8125136 | 0.77 | EGFR (0.50) | EGFRPTGS2SMN1; SMN2AKR1C3MIF | |
| SCHEMBL8125134 | 0.77 | EGFR (0.50) | EGFRPTGS2SMN1; SMN2AKR1C3MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997044316-A9 | CATALYTIC ASYMMETRIC AMINOHYDROXYLATION OF OLEFINS WITH SULFONAMIDES | — | 1998-04-09 | — | — | WO | disclosed |
| WO-1997044316-A1 | CATALYTIC ASYMMETRIC AMINOHYDROXYLATION OF OLEFINS WITH SULFONAMIDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-11-27 | — | — | WO | disclosed |