Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572099 | 1.00 | SCN5A (0.39) | SCN5AKCNH2POLBCACNA1FMAPK1 | |
| SCHEMBL8577579 | 1.00 | SCN5A (0.39) | SCN5AKCNH2POLBCACNA1FMAPK1 | |
| SCHEMBL8572107 | 1.00 | SCN5A (0.39) | SCN5AKCNH2POLBCACNA1FMAPK1 | |
| SCHEMBL8572102 | 1.00 | SCN5A (0.39) | SCN5AKCNH2POLBCACNA1FMAPK1 | |
| Hydrochloric Acid SCHEMBL7500649 | 0.99 | SCN5A (0.39) | SCN5AKCNH2POLBCACNA1FMAPK1 | |
| Hydrochloric Acid SCHEMBL7500357 | 0.99 | SCN5A (0.39) | SCN5AKCNH2POLBCACNA1FMAPK1 | |
| Hydrochloric Acid SCHEMBL7502658 | 0.99 | SCN5A (0.39) | SCN5AKCNH2POLBCACNA1FMAPK1 | |
| Hydrochloric Acid SCHEMBL7500362 | 0.99 | SCN5A (0.39) | SCN5AKCNH2POLBCACNA1FMAPK1 | |
| Hydrochloric Acid SCHEMBL7500643 | 0.99 | SCN5A (0.39) | SCN5AKCNH2POLBCACNA1FMAPK1 | |
| SCHEMBL6169413 | 0.94 | SCN5A (0.38) | SCN5AKCNH2POLBCACNA1FMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | claimed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | claimed |
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |