Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389910 | 0.98 | SMN1; SMN2 (0.50) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL853295 | 0.92 | SMN1; SMN2 (0.46) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL198576 | 0.89 | TSHR (0.44) | LMNAHSD17B10TSHRTHRBMAPT | |
| SCHEMBL198971 | 0.89 | TSHR (0.44) | LMNAHSD17B10TSHRTHRBMAPT | |
| SCHEMBL980876 | 0.89 | TSHR (0.44) | LMNAHSD17B10TSHRTHRBMAPT | |
| SCHEMBL202073 | 0.89 | TSHR (0.44) | LMNAHSD17B10TSHRTHRBMAPT | |
| SCHEMBL198791 | 0.89 | TSHR (0.44) | LMNAHSD17B10TSHRTHRBMAPT | |
| SCHEMBL199912 | 0.89 | TSHR (0.44) | LMNAHSD17B10TSHRTHRBMAPT | |
| SCHEMBL199021 | 0.89 | TSHR (0.44) | LMNAHSD17B10TSHRTHRBMAPT | |
| SCHEMBL198324 | 0.89 | TSHR (0.44) | LMNAHSD17B10TSHRTHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753707-A | TREATING SKIN DISORDER, DERMATITIS, ROUGH SKIN; BARRIER FUNCTION | KAO CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |