Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 5/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.33 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.33 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8561939 | 0.99 | KCNH2 (0.40) | KCNH2SCN5ATOP1PIM1CDK2 | |
| SCHEMBL5570863 | 0.93 | KCNH2 (0.48) | KCNH2SCN5ATOP1PIM1CDK2 | |
| SCHEMBL5567931 | 0.93 | KCNH2 (0.48) | KCNH2SCN5ATOP1PIM1CDK2 | |
| SCHEMBL5278078 | 0.93 | KCNH2 (0.48) | KCNH2SCN5ATOP1PIM1CDK2 | |
| Hydrochloric Acid SCHEMBL7507134 | 0.93 | KCNH2 (0.47) | KCNH2SCN5ATOP1PIM1CDK2 | |
| SCHEMBL8567585 | 0.92 | KCNH2 (0.43) | KCNH2SCN5ATOP1PIM1CDK2 | |
| SCHEMBL8600110 | 0.91 | KCNH2 (0.42) | KCNH2SCN5ATOP1PIM1CDK2 | |
| SCHEMBL8563854 | 0.91 | SCN5A (0.38) | KCNH2SCN5A | |
| Hydrochloric Acid SCHEMBL7494375 | 0.91 | KCNH2 (0.42) | KCNH2SCN5ATOP1PIM1CDK2 | |
| Hydrochloric Acid SCHEMBL7545787 | 0.90 | KCNH2 (0.41) | KCNH2SCN5ATOP1PIM1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | claimed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | claimed |
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |