Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579077 | 0.93 | KDM4E (0.39) | KMT2AMEN1SMN1; SMN2GAAKDM4E | |
| SCHEMBL8576979 | 0.89 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2GAAKDM4E | |
| SCHEMBL8576766 | 0.85 | SMN1; SMN2 (0.34) | KMT2AMEN1SMN1; SMN2GAAKDM4E | |
| SCHEMBL8578144 | 0.85 | KMT2A (0.47) | KMT2AMEN1SMN1; SMN2GAAKDM4E | |
| SCHEMBL4488516 | 0.84 | KDM4E (0.37) | KMT2AMEN1SMN1; SMN2GAAKDM4E | |
| SCHEMBL8578473 | 0.83 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2GAAKDM4E | |
| SCHEMBL8577972 | 0.82 | KMT2A (0.39) | KMT2AMEN1SMN1; SMN2GAAKDM4E | |
| SCHEMBL8578898 | 0.81 | KMT2A (0.47) | KMT2AMEN1SMN1; SMN2GAAKDM4E | |
| SCHEMBL8576874 | 0.81 | MEN1 (0.35) | KMT2AMEN1GAAKDM4EPOLB | |
| SCHEMBL8578556 | 0.81 | KMT2A (0.47) | KMT2AMEN1SMN1; SMN2GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719310-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-17 | — | — | US | disclosed |
| US-5610122-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |