Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 8/20 | 0.37 |
| ▸ | CA2 | P00918 | 8/20 | 0.37 |
| ▸ | CA9 | Q16790 | 7/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576723 | 1.00 | HTT (0.54) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL816285 | 0.97 | TSHR (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL130731 | 0.97 | TSHR (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL817599 | 0.97 | TSHR (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL816140 | 0.97 | TSHR (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL816279 | 0.97 | TSHR (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL818096 | 0.97 | TSHR (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL816419 | 0.97 | TSHR (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL820419 | 0.97 | TSHR (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL816971 | 0.97 | TSHR (0.50) | HTTMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801258-A | Amide derivatives and dermatologic preparations containing the same | KAO CORPORATION (JP) | 1998-09-01 | — | — | US | disclosed |
| US-5753707-A | TREATING SKIN DISORDER, DERMATITIS, ROUGH SKIN; BARRIER FUNCTION | KAO CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0623124-B1 | AMIDE DERIVATIVES AND DERMATOLOGIC PREPARATIONS CONTAINING THE SAME | KAO CORP (JP) | 1998-02-18 | — | — | EP | disclosed |
| US-5659052-A | APPLYING TO SKIN TO IMPROVE BARRIER FUNCTIONS OF HORNY LAYER | KAO CORPORATION (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0761644-A2 | Amide derivatives and their use in cosmetic composition | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |
| EP-0623124-A1 | AMIDE DERIVATIVES AND DERMATOLOGIC PREPARATIONS CONTAINING THE SAME | Kao Corporation (JP) | 1994-11-09 | — | — | EP | disclosed |
| WO-1994012490-A2 | AMIDE DERIVATIVES AND DERMATOLOGIC PREPARATIONS CONTAINING THE SAME | KAO CORPORATION (JP) | 1994-06-09 | — | — | WO | disclosed |