SCHEMBL8577197

SCHEMBL8577197

Nc1ccccc1OCCCS(=O)(=O)CCO

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.51
CYP2C19 P33261 2/20 0.51
CYP2C9 P11712 1/20 0.51
ALDH1A1 P00352 7/20 0.43
LMNA P02545 6/20 0.40
RECQL P46063 2/20 0.40
APP P05067 1/20 0.37
TDP1 Q9NUW8 2/20 0.35
ADRA2B P18089 1/20 0.35
PTGS1 P23219 1/20 0.35
POLB P06746 3/20 0.35
NPC1 O15118 2/20 0.35
PTK2B Q14289 1/20 0.35
KDM4E B2RXH2 2/20 0.34
MAPT P10636 3/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CYP3A4 P08684 2/20 0.34
MEN1 O00255 1/20 0.34
NR1I2 O75469 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8573836 0.92 CYP1A2 (0.49) CYP1A2CYP2C19CYP2C9ALDH1A1LMNA
SCHEMBL8579261 0.84 CYP1A2 (0.36) CYP1A2CYP2C19CYP2C9ALDH1A1LMNA
SCHEMBL1485823 0.82 CYP1A2 (0.56) CYP1A2CYP2C19CYP2C9ALDH1A1LMNA
SCHEMBL9294260 0.81 CYP1A2 (0.54) CYP1A2CYP2C19CYP2C9ALDH1A1LMNA
SCHEMBL17197393 0.80 CYP1A2 (0.62) CYP1A2CYP2C19CYP2C9ALDH1A1LMNA
SCHEMBL13884056 0.79 CYP1A2 (0.66) CYP1A2CYP2C19CYP2C9ALDH1A1LMNA
SCHEMBL8579133 0.79 S1PR3 (0.40) CYP1A2CYP2C19CYP2C9ALDH1A1LMNA
SCHEMBL9294258 0.78 CYP1A2 (0.54) CYP1A2CYP2C19CYP2C9ALDH1A1LMNA
SCHEMBL29495066 0.78 CYP1A2 (0.54) CYP1A2CYP2C19CYP2C9ALDH1A1LMNA
SCHEMBL2447323 0.78 CYP1A2 (0.54) CYP1A2CYP2C19CYP2C9ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744622-A water-soluble, fiber-reactive anthraquinone compounds HOECHST AKTIENGESELLSCHAFT (DE) 1998-04-28 US disclosed
EP-0501266-B1 Bifunctional reactive dyes BAYER AG (DE) 1995-06-21 EP disclosed
EP-0501266-A1 Bifunctional reactive dyes BAYER AG (DE) 1992-09-02 EP disclosed