Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2120462 | 0.83 | NOTUM (0.60) | NOTUMRAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL15695539 | 0.81 | NPC1 (0.50) | NOTUMRAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL1313860 | 0.80 | CYP1A2 (0.61) | NOTUMRAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL4275449 | 0.80 | NOTUM (0.60) | NOTUMRAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL31532187 | 0.80 | NOTUM (0.55) | NOTUMRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL16915404 | 0.80 | NOTUM (0.55) | NOTUMRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL20845555 | 0.75 | NOTUM (0.67) | NOTUMRAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL1313626 | 0.75 | NOTUM (1.00) | NOTUMRAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL20163150 | 0.75 | SMN1; SMN2 (0.58) | RAB9ASMN1; SMN2MAPTNPC1CYP1A2 | |
| SCHEMBL27614908 | 0.74 | NOTUM (0.53) | NOTUMRAB9ASMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015541-A1 | NOVEL ISOXAZOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND A PROCESS FOR THE PREPARATION OF THE NOVEL COMPOUNDS | EGIS Gyógyszergyár Rt. (HU) | 1998-04-16 | — | — | WO | disclosed |