Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627547 | 0.85 | KDM4E (0.37) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL8601039 | 0.84 | KDM4E (0.36) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL7788430 | 0.77 | KDM4E (0.40) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL1290285 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL12501961 | 0.76 | KDM4E (0.38) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL1289979 | 0.75 | GAA (0.39) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL12502207 | 0.75 | CDK5 (0.42) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL1290073 | 0.75 | SMN1; SMN2 (0.42) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL8570051 | 0.74 | KDM4E (0.40) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL8573258 | 0.74 | KDM4E (0.35) | KDM4EALDH1A1GAAGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |