Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578736 | 1.00 | CNR1 (0.72) | CNR1KDM4EEPHX2ALDH1A1HPGD | |
| SCHEMBL8579026 | 1.00 | CNR1 (0.72) | CNR1KDM4EEPHX2ALDH1A1HPGD | |
| SCHEMBL8599223 | 1.00 | CNR1 (0.72) | CNR1KDM4EEPHX2ALDH1A1HPGD | |
| SCHEMBL16619266 | 0.93 | EPHX2 (0.72) | CNR1KDM4EEPHX2ALDH1A1HPGD | |
| SCHEMBL16619267 | 0.93 | EPHX2 (0.72) | CNR1KDM4EEPHX2ALDH1A1HPGD | |
| SCHEMBL14849281 | 0.92 | CNR1 (0.85) | CNR1KDM4EEPHX2ALDH1A1HPGD | |
| SCHEMBL6286826 | 0.92 | CNR1 (0.85) | CNR1KDM4EEPHX2ALDH1A1HPGD | |
| SCHEMBL15007722 | 0.92 | CNR1 (0.85) | CNR1KDM4EEPHX2ALDH1A1HPGD | |
| SCHEMBL6286194 | 0.92 | CNR1 (0.85) | CNR1KDM4EEPHX2ALDH1A1HPGD | |
| SCHEMBL31438099 | 0.92 | CNR1 (0.85) | CNR1KDM4EEPHX2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753707-A | TREATING SKIN DISORDER, DERMATITIS, ROUGH SKIN; BARRIER FUNCTION | KAO CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0761644-A2 | Amide derivatives and their use in cosmetic composition | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |