Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA4 | P22748 | 3/20 | 0.45 |
| ▸ | CA6 | P23280 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30253662 | 0.85 | ERN1 (0.49) | KDM4ETSHRTP53MYCCA12 | |
| SCHEMBL1302677 | 0.85 | ERN1 (0.49) | KDM4ETSHRTP53MYCCA12 | |
| Hydrochloric Acid SCHEMBL7539954 | 0.83 | ERN1 (0.47) | KDM4ETSHRTP53MYCCA12 | |
| SCHEMBL29598455 | 0.83 | KDM4E (0.47) | KDM4ETSHRTP53MYCCA12 | |
| SCHEMBL605638 | 0.83 | KDM4E (0.47) | KDM4ETSHRTP53MYCCA12 | |
| SCHEMBL25282099 | 0.83 | KDM4E (0.47) | KDM4ETSHRTP53MYCCA12 | |
| Lithium SCHEMBL31456603 | 0.82 | KDM4E (0.46) | KDM4ETSHRTP53MYCCA12 | |
| Ethylene Glycol SCHEMBL27849971 | 0.81 | KDM4E (0.42) | KDM4ETSHRTP53MYCCA12 | |
| SCHEMBL6269466 | 0.80 | MYC (0.45) | KDM4ETSHRTP53MYCCA12 | |
| SCHEMBL6269470 | 0.80 | MYC (0.45) | KDM4ETSHRTP53MYCCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792840-A | SUBSTITUTED GLUCOPYRANOSYL PHOSPHATES | SANKYO COMPANY, LIMITED (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0437016-B1 | Lipid A analogues having immunoactivating and anti-tumour activity | SANKYO CO (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0437016-A2 | Lipid A analogues having immunoactivating and anti-tumour activity | Sankyo Company Limited (JP) | 1991-07-17 | — | — | EP | disclosed |