SCHEMBL8579690

SCHEMBL8579690

CCCCCCCCCCCCCCCCC1=NCCN1CC

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 2/20 0.35
TOP2B Q02880 2/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
SCD O00767 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9164590 1.00 TOP2A (0.35) TOP2ATOP2BMEN1KMT2ASCD
SCHEMBL10616840 1.00 TOP2A (0.35) TOP2ATOP2BMEN1KMT2ASCD
SCHEMBL10617494 1.00 TOP2A (0.35) TOP2ATOP2BMEN1KMT2ASCD
SCHEMBL10792536 1.00 TOP2A (0.35) TOP2ATOP2BMEN1KMT2ASCD
SCHEMBL9168417 1.00 TOP2A (0.35) TOP2ATOP2BMEN1KMT2ASCD
Hydrochloric Acid SCHEMBL11117732 0.98 TOP2A (0.36) TOP2ATOP2BMEN1KMT2ASCD
Ammonia Solution, Strong SCHEMBL2289227 0.98 TOP2A (0.34) TOP2ATOP2BMEN1KMT2ASCD
Diethylamine SCHEMBL10618390 0.92 TOP2A (0.34) TOP2ATOP2BMEN1KMT2A
SCHEMBL27319099 0.92 SCD (0.33) TOP2ATOP2BMEN1KMT2ASCD
SCHEMBL27315899 0.92 SCD (0.33) TOP2ATOP2BMEN1KMT2ASCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0265187-B1 Detergent plus softener with imidazoline ingredient PROCTER & GAMBLE (US) 1994-03-09 EP claimed
US-4770815-A ANIONIC SURFACTANTS; OPTIONALLY CONTAINING CLAYS, BUILDERS, CHELATING AGENTS AND-OR BLEACHING AGENTS THE PROCTER & GAMBLE COMPANY (US) 1988-09-13 US claimed
EP-0265187-A2 Detergent plus softener with imidazoline ingredient THE PROCTER & GAMBLE COMPANY (US) 1988-04-27 EP claimed
US-10988900-B2 Tissue comprising a softening composition KIMBERLY-CLARK WORLDWIDE, INC. (US) 2021-04-27 US disclosed
US-10794007-B2 Lotion treated through-air dried tissue KIMBERLY-CLARK WORLDWIDE, INC. (US) 2020-10-06 US disclosed
US-20190078262-A1 LOTION TREATED THROUGH-AIR DRIED TISSUE KIMBERLY CLARK CO (US) 2019-03-14 US disclosed
US-20190071822-A1 TISSUE COMPRISING A SOFTENING COMPOSITION KIMBERLY CLARK CO (US) 2019-03-07 US disclosed
US-5854200-A Rinse added fabric softener compositions containing antioxidants for sun-fade protection for fabrics THE PROCTER & GAMBLE COMPANY (US) 1998-12-29 US disclosed
US-5723435-A Rinse added fabric softener compositions containing antioxidants for sun-fade protection fabrics THE PROCTER & GAMBLE COMPANY (US) 1998-03-03 US disclosed
US-5705474-A MIXTURE INCLUDES 2-PHENYLBENZOTRIAZOLE DERIVATIVE THE PROCTER & GAMBLE COMPANY (US) 1998-01-06 US disclosed
EP-0431652-B1 Fabric softening and anti-static compositions PROCTER & GAMBLE (US) 1995-10-25 EP disclosed
EP-0265187-B1 Detergent plus softener with imidazoline ingredient PROCTER & GAMBLE (US) 1994-03-09 EP disclosed
US-5154841-A Cyclizing a polyamine with a fatty acid, ester, acyl halide or anhydride, followed by catalytic esterification with fatty acid ester or glycerides; titanium or tin alkoxides, salts, halides or alkyl halide as catalysts THE PROCTER & GAMBLE COMPANY (US) 1992-10-13 US disclosed
US-5116520-A FABRIC SOFTENING AND ANTI-STATIC COMPOSITIONS CONTAINING A QUATERNIZED DI-SUBSTITUTED IMIDAZOLINE ESTER FABRIC SOFTENING COMPOUND WITH A NONIONIC FABRIC SOFTENING COMPOUND THE PROCTER & GAMBLE CO. (US) 1992-05-26 US disclosed
EP-0431652-A1 Fabric softening and anti-static compositions THE PROCTER & GAMBLE COMPANY (US) 1991-06-12 EP disclosed
US-5013846-A Process for preparing substituted imidazoline fabric conditioning compounds THE PROCTER & GAMBLE COMPANY (US) 1991-05-07 US disclosed
EP-0375029-A2 Process for preparing substituted imidazoline fabric conditioning compounds THE PROCTER & GAMBLE COMPANY (US) 1990-06-27 EP disclosed
EP-0326222-A2 Process for preparing substituted imidazoline fabric conditioning compounds THE PROCTER & GAMBLE COMPANY (US) 1989-08-02 EP disclosed
US-4770815-A ANIONIC SURFACTANTS; OPTIONALLY CONTAINING CLAYS, BUILDERS, CHELATING AGENTS AND-OR BLEACHING AGENTS THE PROCTER & GAMBLE COMPANY (US) 1988-09-13 US disclosed
EP-0265187-A2 Detergent plus softener with imidazoline ingredient THE PROCTER & GAMBLE COMPANY (US) 1988-04-27 EP disclosed