Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8594670 | 0.91 | ABCB1 (0.51) | ABCB1CYP3A4CYP2C9CYP2C19HTT | |
| SCHEMBL3766544 | 0.91 | ABCB1 (0.51) | ABCB1CYP3A4CYP2C9CYP2C19HTT | |
| SCHEMBL14078518 | 0.90 | ABCB1 (0.50) | ABCB1CYP3A4CYP2C9CYP2C19HTT | |
| SCHEMBL3771854 | 0.88 | ABCB1 (0.48) | ABCB1CYP3A4CYP2C9CYP2C19HTT | |
| SCHEMBL16368762 | 0.88 | ABCB1 (0.48) | ABCB1CYP3A4CYP2C9CYP2C19HTT | |
| SCHEMBL13003212 | 0.88 | ABCB1 (0.48) | ABCB1CYP3A4CYP2C9CYP2C19HTT | |
| SCHEMBL13060027 | 0.88 | ABCB1 (0.48) | ABCB1CYP3A4CYP2C9CYP2C19HTT | |
| SCHEMBL3769756 | 0.85 | ABCB1 (0.51) | ABCB1CYP3A4CYP2C9CYP2C19HTT | |
| SCHEMBL8617673 | 0.85 | ABCB1 (0.51) | ABCB1CYP3A4CYP2C9CYP2C19HTT | |
| SCHEMBL13003215 | 0.84 | ABCB1 (0.51) | ABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455375-A2 | Diacylhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-05-23 | — | — | EP | disclosed |