Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581702 | 1.00 | MEN1 (0.33) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL5967595 | 0.84 | ZDHHC7 (0.32) | MEN1KMT2A | |
| SCHEMBL5967597 | 0.80 | TLR2 (0.32) | — | |
| SCHEMBL8581695 | 0.80 | TLR2 (0.34) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL8579632 | 0.80 | TLR2 (0.34) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL5967572 | 0.78 | MME (0.33) | — | |
| SCHEMBL5967623 | 0.77 | — | — | |
| SCHEMBL8579507 | 0.76 | TLR2 (0.35) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL8582094 | 0.76 | CA12 (0.40) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL8581441 | 0.76 | MEN1 (0.32) | MEN1KMT2ACYP2C9ALOX15CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705527-A | VASODILATORS AND ANGINA PECTORIS | SANKYO COMPANY, LIMITED (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0641769-B1 | AMINO ACID DERIVATIVE | SANKYO CO (JP) | 1997-01-29 | — | — | EP | disclosed |
| EP-0641769-A1 | AMINO ACID DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | disclosed |