Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581999 | 1.00 | IRAK4 (0.38) | IRAK4KDM4ECYP3A4CHRM4CYP2C9 | |
| SCHEMBL8486785 | 0.84 | BTK (0.42) | IRAK4KDM4EBTK | |
| SCHEMBL8490025 | 0.84 | IRAK4 (0.45) | IRAK4KDM4ECYP3A4CHRM4CYP2C9 | |
| SCHEMBL8487365 | 0.84 | BTK (0.42) | IRAK4KDM4EBTK | |
| SCHEMBL8746781 | 0.83 | BTK (0.46) | IRAK4KDM4EBTK | |
| SCHEMBL8746780 | 0.83 | BTK (0.46) | IRAK4KDM4EBTK | |
| SCHEMBL8483434 | 0.82 | BTK (0.43) | IRAK4KDM4ECYP3A4CHRM4CYP2C9 | |
| SCHEMBL8483437 | 0.82 | BTK (0.43) | IRAK4KDM4ECYP3A4CHRM4CYP2C9 | |
| SCHEMBL8120612 | 0.82 | IRAK4 (0.37) | IRAK4KDM4ECYP3A4CHRM4CYP2C9 | |
| SCHEMBL7198151 | 0.82 | IRAK4 (0.37) | IRAK4KDM4ECYP3A4CHRM4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031072-A1 | CYCLOHEXYLAMINE ARTHROPODICIDES AND FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-06-24 | — | — | WO | disclosed |