Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582990 | 1.00 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL8587130 | 0.75 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL7621951 | 0.75 | SMN1; SMN2 (0.44) | MEN1KMT2ASMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL8587135 | 0.75 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL7621956 | 0.75 | SMN1; SMN2 (0.44) | MEN1KMT2ASMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL20876285 | 0.75 | KMT2A (0.52) | MEN1KMT2ASMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL1806495 | 0.75 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL8585910 | 0.74 | CYP19A1 (0.42) | MEN1KMT2AMAPK1LMNACYP19A1 | |
| SCHEMBL8881575 | 0.74 | CYP19A1 (0.42) | MEN1KMT2AMAPK1LMNACYP19A1 | |
| SCHEMBL2799509 | 0.73 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998020878-A1 | 5-[φ-(SUBSTITUTED ARYL)ALKENYLENE AND ALKYNYLENE]-2,4-DIAMINOPYRIMIDINES AS PESTICIDES | FMC CORPORATION (US) | 1998-05-22 | — | — | WO | disclosed |
| US-5696259-A | 2,4-diamino-5-iodopyrimidines useful as pesticide intermediates | FMC CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| US-5622954-A | INSECTICIDE | FMC CORPORATION (US) | 1997-04-22 | — | — | US | disclosed |