SCHEMBL85842

SCHEMBL85842

CC#CCNC(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10739303 0.80 KDM4E (0.43)
SCHEMBL11573312 0.80 EPHX1 (0.33)
SCHEMBL1694479 0.78
SCHEMBL13978172 0.78
SCHEMBL12061816 0.77
SCHEMBL8396032 0.76
SCHEMBL7442539 0.76
SCHEMBL9029974 0.76
SCHEMBL26448806 0.76
SCHEMBL17188612 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11788138-B2 Nucleic acid sequencing using affinity reagents MGI TECH CO., LTD. (CN) 2023-10-17 US disclosed
US-20180223358-A1 STEPWISE SEQUENCING BY NON-LABELED REVERSIBLE TERMINATORS OR NATURAL NUCLEOTIDES MGI TECH CO., LTD. (CN) 2018-08-09 US disclosed
EP-1699760-B1 ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS MERCK SHARP & DOHME (US) 2017-05-17 EP disclosed
US-20160032376-A1 NUCLEOTIDE ANALOGS FOR SEQUENCING IBIS BIOSCIENCES, INC. 2016-02-04 US disclosed
US-8912318-B2 Nucleobase-functionalized conformationally restricted nucleotides and oligonucleotides for targeting nucleic acids UNIVERSITY OF IDAHO (US) 2014-12-16 US disclosed
WO-2014086751-A1 USE OF SUBSTITUTED 1-(ARYL ETHYNYL)-, 1-(HETEROARYL ETHYNYL)-, 1-(HETEROCYCLYL ETHYNYL)- AND 1-(CYLOALKENYL ETHYNYL)-CYCLOHEXANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2014-06-12 WO disclosed
WO-2013073602-A1 NUCLEIC ACID FRAGMENT BINDING TO TARGET PROTEIN 独立行政法人理化学研究所 (JP) 2013-05-23 WO disclosed
US-20120196295-A1 UV Excitable Fluorescent Energy Transfer Dyes Life Technologies Corporation (US) 2012-08-02 US disclosed
US-8129529-B2 UV excitable fluorescent energy transfer dyes APPLIED BIOSYSTEMS, LLC (US) 2012-03-06 US disclosed
US-20110077415-A1 UV Excitable Fluorescent Energy Transfer Dyes Life Technologies Corporation (US) 2011-03-31 US disclosed
US-7550570-B2 Labeling nucleotide sequences with rhodamine dye APPLIED BIOSYSTEMS, LLC. (US) 2009-06-23 US disclosed
US-20090093623-A1 4,7-DICHLORORHODAMINE DYES APPLIED BIOSYSTEMS INC. (US) 2009-04-09 US disclosed
US-20090062543-A1 UV EXCITABLE FLUORESCENT ENERGY TRANSFER DYES APPLIED BIOSYSTEMS INC. (US) 2009-03-05 US disclosed
US-20090031506-A1 UV Excitable Fluorescent Energy Transfer Dyes APPLERA CORPORATION (US) 2009-02-05 US disclosed
US-7402671-B2 UV excitable fluorescent energy transfer dyes APPLERA CORPORATION (US) 2008-07-22 US disclosed
WO-2008079610-A2 NOVEL ACETYL-COA CARBOXYLASE (ACC) INHIBITORS AND THEIR USE IN DIABETES, OBESITY AND METABOLIC SYNDROME ABBOTT LABORATORIES (US) 2008-07-03 WO disclosed
US-7378517-B2 UV excitable energy transfer reagents APPLERA CORPORATION (US) 2008-05-27 US disclosed
US-7179906-B2 Asymmetric benzoxanthene dyes APPLERA CORPORATION (US) 2007-02-20 US disclosed
US-7169939-B2 Energy transfer dyes with enhanced fluorescence APPLERA CORPORATION (US) 2007-01-30 US disclosed
US-7157572-B2 UV excitable energy transfer reagents APPLERA CORPORATION (US) 2007-01-02 US disclosed