SCHEMBL8584747

SCHEMBL8584747

CC(C)(C)c1cccc(C(C)(C)C)c1N1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(c1c(C(C)(C)C)cccc1C(C)(C)C)C5=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 4/20 0.41
▸ NPC1 O15118 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ STAT3 P40763 1/20 0.39
▸ HIF1A Q16665 1/20 0.39
▸ USP2 O75604 4/20 0.37
▸ KMT2A Q03164 4/20 0.37
▸ MEN1 O00255 3/20 0.37
▸ LMNA P02545 2/20 0.37
▸ TP53 P04637 2/20 0.37
▸ L3MBTL1 Q9Y468 2/20 0.37
▸ MAPT P10636 2/20 0.37
▸ HTT P42858 2/20 0.37
▸ THRB P10828 1/20 0.37
▸ TLR9 Q9NR96 1/20 0.37
▸ RGS12 O14924 1/20 0.37
▸ RECQL P46063 1/20 0.37
▸ S1PR2 O95136 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ ANPEP P15144 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29396950 0.79 DPP4 (0.57) TERTNPC1RAB9ASTAT3HIF1A
SCHEMBL272816 0.79 DPP4 (0.57) TERTNPC1RAB9ASTAT3HIF1A
SCHEMBL23135498 0.78 DPP4 (0.41) TERTNPC1RAB9ASTAT3HIF1A
SCHEMBL8070665 0.77 ANPEP (0.59) TERTNPC1RAB9ASTAT3HIF1A
SCHEMBL17033240 0.76 TP53 (0.45) TERTNPC1RAB9ASTAT3HIF1A
SCHEMBL9149839 0.76 KMT2A (0.46) TERTNPC1RAB9AUSP2KMT2A
SCHEMBL2921938 0.76 KMT2A (0.46) NPC1RAB9AKMT2AMEN1L3MBTL1
SCHEMBL3438530 0.75 ANPEP (0.60) TERTNPC1RAB9ASTAT3HIF1A
SCHEMBL13478139 0.75 ANPEP (0.60) TERTNPC1RAB9ASTAT3HIF1A
SCHEMBL29369271 0.75 ANPEP (0.60) TERTNPC1RAB9ASTAT3HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9496462-B2 Optoelectronic semiconductor chip OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2016-11-15 — — US disclosed
US-9496462-B2 Optoelectronic semiconductor chip OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2016-11-15 — — US disclosed
US-20150349215-A1 Optoelectronic Semiconductor Chip OSRAM OLED GMBH (DE) 2015-12-03 — — US disclosed
US-20150349215-A1 Optoelectronic Semiconductor Chip OSRAM OLED GMBH (DE) 2015-12-03 — — US disclosed
WO-2014108289-A1 OPTOELECTRONIC SEMICONDUCTOR CHIP OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2014-07-17 — — WO disclosed
US-5846666-A Electroluminescent devices XEROX CORPORATION (US) 1998-12-08 — — US disclosed
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