Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HK2 | P52789 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.30 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6269405 | 0.85 | KDM4E (0.30) | KDM4EHTTHSD17B10 | |
| SCHEMBL28916969 | 0.81 | KMT2A (0.35) | GAAMAPTALDH1A1NPSR1KDM4E | |
| SCHEMBL28586739 | 0.81 | SCN1A (0.36) | GAAMAPTALDH1A1PKMSCN1A | |
| SCHEMBL1001072 | 0.80 | — | — | |
| SCHEMBL28048789 | 0.80 | GAA (0.33) | GAAHK2MAPTALDH1A1PKM | |
| SCHEMBL28589256 | 0.79 | TSHR (0.38) | GAAMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28581190 | 0.78 | MAPT (0.39) | GAAMAPTALDH1A1PKMKDM4E | |
| SCHEMBL27774042 | 0.77 | — | — | |
| SCHEMBL7684826 | 0.75 | USP2 (0.34) | HK2ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL28796597 | 0.75 | MAOB (0.32) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998031697-A1 | ARYL C-GLYCOSIDE COMPOUNDS AND SULFATED ESTERS THEREOF | SANKYO COMPANY, LIMITED (JP) | 1998-07-23 | — | — | WO | disclosed |