Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7155699 | 1.00 | TSHR (0.37) | TSHRSMN1; SMN2ALDH1A1TDP1ALOX5 | |
| SCHEMBL9232246 | 0.98 | TSHR (0.38) | TSHRSMN1; SMN2ALDH1A1TDP1ALOX5 | |
| SCHEMBL17461572 | 0.91 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL6553153 | 0.89 | TSHR (0.40) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL22852496 | 0.89 | TSHR (0.44) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL17461579 | 0.87 | SMN1; SMN2 (0.37) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL1104607 | 0.83 | SMN1; SMN2 (0.33) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL7875340 | 0.83 | SMN1; SMN2 (0.43) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL16663913 | 0.82 | TSHR (0.47) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL16675416 | 0.82 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10251400-A | — | — | None | — | — | JP | disclosed |
| JP-H10251400-A | ALKYLENE OXIDE OLIGOMER CONTAINING CYCLIC POLAR GROUP AT END GROUP | SUMITOMO CHEM CO LTD | 1998-09-22 | — | — | JP | disclosed |