SCHEMBL8587002

SCHEMBL8587002

CCCCCCCCCCCCCCCCC[S+]([O-])CCCCCCCCCCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.50
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
DNM1 Q05193 5/20 0.38
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC22A1 O15245 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9818219 1.00 TSHR (0.50) TSHRTHRBCES2CES1DNM1
SCHEMBL296474 1.00 TSHR (0.50) TSHRTHRBCES2CES1DNM1
SCHEMBL4791112 1.00 TSHR (0.50) TSHRTHRBCES2CES1DNM1
SCHEMBL3025854 1.00 TSHR (0.50) TSHRTHRBCES2CES1DNM1
SCHEMBL669556 1.00 TSHR (0.50) TSHRTHRBCES2CES1DNM1
SCHEMBL3151593 1.00 TSHR (0.50) TSHRTHRBCES2CES1DNM1
SCHEMBL3155716 1.00 TSHR (0.50) TSHRTHRBCES2CES1DNM1
SCHEMBL3160216 1.00 TSHR (0.50) TSHRTHRBCES2CES1DNM1
SCHEMBL14478066 1.00 TSHR (0.50) TSHRTHRBCES2CES1DNM1
SCHEMBL939615 1.00 TSHR (0.50) TSHRTHRBCES2CES1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8859486-B2 Anhydrous detergent composition comprising a clay mixture processed with quaternary ammonium salts CHURCH & DWIGHT CO., INC. (US) 2014-10-14 US disclosed
US-20140274861-A1 ANHYDROUS DETERGENT COMPOSITION COMPRISING A CLAY MIXTURE PROCESSED WITH QUATERNARY AMMONIUM SALTS CHURCH & DWIGHT CO., INC. (US) 2014-09-18 US disclosed
US-5759980-A ANIONIC, NONIONIC SURFACTANTS, SILICONE SURFACTANT, POLYMER; ELIMINATES SPOTTING BLUE CORAL, INC. (US) 1998-06-02 US disclosed
US-4681704-A REMOVAL OF GREASY SOILS THE PROCTER & GAMBLE COMPANY (US) 1987-07-21 US disclosed
EP-0157443-A1 Detergent composition containing semi-polar nonionic detergent, alkaline earth metal anionic detergent, and amidoalkylbetaine detergent THE PROCTER & GAMBLE COMPANY (US) 1985-10-09 EP disclosed
EP-0034387-B1 MULLS CONTAINING CHAIN STRUCTURE CLAY SUSPENSION AIDS THE PROCTER & GAMBLE COMPANY (US) 1984-10-24 EP disclosed
US-4287080-A Detergent compositions which contain certain tertiary alcohols THE PROCTER & GAMBLE COMPANY (US) 1981-09-01 US disclosed
EP-0034387-A2 Mulls containing chain structure clay suspension aids THE PROCTER & GAMBLE COMPANY (US) 1981-08-26 EP disclosed
US-4264466-A LAUNDRY DETERGENTS THE PROCTER & GAMBLE COMPANY (US) 1981-04-28 US disclosed
US-4133779-A AMINE OXIDE THE PROCTER & GAMBLE COMPANY (US) 1979-01-09 US disclosed