Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | F12 | P00748 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201150 | 0.89 | MAPT (0.51) | KMT2ASMN1; SMN2MEN1CYP1A2CYP2D6 | |
| SCHEMBL8190500 | 0.89 | MAPT (0.51) | KMT2ASMN1; SMN2MEN1CYP1A2CYP2D6 | |
| SCHEMBL8201026 | 0.89 | MAPT (0.51) | KMT2ASMN1; SMN2MEN1CYP1A2CYP2D6 | |
| SCHEMBL8200469 | 0.89 | KMT2A (0.46) | KMT2ASMN1; SMN2MEN1CYP1A2CYP2D6 | |
| SCHEMBL8216532 | 0.85 | MAPT (0.51) | KMT2ASMN1; SMN2MEN1CYP1A2CYP2D6 | |
| SCHEMBL8190514 | 0.85 | MAPT (0.51) | KMT2ASMN1; SMN2MEN1CYP1A2CYP2D6 | |
| SCHEMBL6933189 | 0.84 | KMT2A (0.42) | KMT2ASMN1; SMN2MEN1CYP1A2CYP2D6 | |
| SCHEMBL6936897 | 0.83 | KMT2A (0.42) | KMT2ASMN1; SMN2MEN1CYP1A2CYP2D6 | |
| SCHEMBL6940301 | 0.83 | KMT2A (0.41) | KMT2ASMN1; SMN2MEN1CYP1A2CYP2D6 | |
| SCHEMBL9128479 | 0.83 | KMT2A (0.39) | KMT2ASMN1; SMN2MEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10245363-A | — | — | None | — | — | JP | disclosed |
| WO-1999035132-A1 | HETEROCYCLIC COMPOUNDS | GLAXO GROUP LIMITED (GB) | 1999-07-15 | — | — | WO | disclosed |
| JP-H10245363-A | PHENYL ESTER AND FERRIDIELECTRIC LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | MITSUBISHI GAS CHEM CO INC | 1998-09-14 | — | — | JP | disclosed |