⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8856019 | 0.81 | KDM4E (0.38) | — | |
| SCHEMBL3132700 | 0.80 | KDM4E (0.41) | — | |
| SCHEMBL17877073 | 0.80 | KDM4E (0.41) | — | |
| SCHEMBL6669972 | 0.78 | — | — | |
| SCHEMBL4123213 | 0.76 | — | — | |
| SCHEMBL10875897 | 0.76 | — | — | |
| SCHEMBL14356161 | 0.76 | — | — | |
| SCHEMBL9066008 | 0.74 | KDM4E (0.37) | — | |
| SCHEMBL9065677 | 0.74 | KDM4E (0.37) | — | |
| SCHEMBL11576933 | 0.74 | KDM4E (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5717075-A | FORMED BY REACTING MEMBRANE THAT HAS BOUND CARBOXYLIC ACID GROUPS WITH 2-ETHYL-5'-PHENYLISOXAZOLIUM SULFONATE | THE PERKIN-ELMER CORPORATION (US) | 1998-02-10 | — | — | US | disclosed |
| EP-0677058-A4 | SUPPORT AND METHOD FOR IMMOBILIZING POLYPEPTIDES. | APPLIED BIOSYSTEMS (US) | 1997-09-24 | — | — | EP | disclosed |
| US-5602207-A | A POLYVINYLIDENE FLUORIDE MEMBRANE HAVING SURFACE-ATTACHED ENOL ESTER GROUPS AND SURFACE ATTACHED SULFONATE GROUPS | THE PERKIN-ELMER CORPORATION (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0677058-A1 | SUPPORT AND METHOD FOR IMMOBILIZING POLYPEPTIDES | THE PERKIN-ELMER CORPORATION (US) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994015948-A1 | SUPPORT AND METHOD FOR IMMOBILIZING POLYPEPTIDES | APPLIED BIOSYSTEMS, INC. (US) | 1994-07-21 | — | — | WO | disclosed |
| US-4918231-A | REACTING A SILYLATED CYANOHYDRIN WITH GRIGNARD REAGENT; TREATING WITH REDUCING AGENT; HYDROLYSIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-04-17 | — | — | US | disclosed |
| EP-0170517-B1 | PROCESS FOR THE PRODUCTION OF 1,2-AMINO ALCOHOLS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-12-27 | — | — | EP | disclosed |
| EP-0170517-A2 | Process for the production of 1,2-amino alcohols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-02-05 | — | — | EP | disclosed |