SCHEMBL8587784

SCHEMBL8587784

C=COC(=O)NOC(=O)O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27553831 0.79 PLAU (0.34) PLAU
SCHEMBL328725 0.73
SCHEMBL6903504 0.72
SCHEMBL12807130 0.71 MAPT (0.43)
SCHEMBL2365102 0.70
SCHEMBL35244 0.70
SCHEMBL28119778 0.69
SCHEMBL27803254 0.68
Ethylene SCHEMBL37185 0.68
SCHEMBL6320805 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0559820-B1 SURFACE COATING OF POLYMER OBJECTS BAUSCH & LOMB (US) 1998-02-18 EP disclosed
EP-0560916-B1 Method of molding of silicon-containing contact lenses BAUSCH & LOMB (US) 1997-02-05 EP disclosed
EP-0559809-B1 SURFACE MODIFICATION OF POLYMER OBJECTS BAUSCH & LOMB (US) 1996-11-06 EP disclosed
EP-0559784-B1 SURFACE-ACTIVE MACROMONOMERS BAUSCH & LOMB (US) 1996-08-21 EP disclosed
US-5525691-A Surface modification of polymeric objects BAUSCH & LOMB INCORPORATED (US) 1996-06-11 US disclosed
US-5364918-A Surface modification of polymer objects BAUSCH & LOMB INCORPORATED (US) 1994-11-15 US disclosed
US-5274008-A Using a mold surface having improved wettability made of a copolymer of an acrylic mononitrile and a monomer that enhances melt processability; contact lenses BAUSCH & LOMB INCORPORATED (US) 1993-12-28 US disclosed
EP-0560916-A1 MOLD MATERIALS FOR SILICONE CONTAINING LENS MATERIALS. BAUSCH & LOMB (US) 1993-09-22 EP disclosed
EP-0559820-A1 SURFACE COATING OF POLYMER OBJECTS BAUSCH & LOMB INCORPORATED (US) 1993-09-15 EP disclosed
EP-0559784-A1 SURFACE-ACTIVE MACROMONOMERS. BAUSCH & LOMB (US) 1993-09-15 EP disclosed
EP-0559809-A1 SURFACE MODIFICATION OF POLYMER OBJECTS. BAUSCH & LOMB (US) 1993-09-15 EP disclosed
US-5219965-A Adding polymerizable surfactant to monomer mixture; contact lenses BAUSCH & LOMB INCORPORATED (US) 1993-06-15 US disclosed
US-5177165-A Contact lenses BAUSCH & LOMB INCORPORATED (US) 1993-01-05 US disclosed
US-5158717-A Contact lenses from copolymerizing silicone and hydrophilic monomers in mold produced from an acrylonitrile copolymer resin; melt processability, wettability BAUSCH & LOMB INCORPORATED (US) 1992-10-27 US disclosed
US-5135297-A Immersing a contact lens in an aqueous dispersion of a polymerizable surfactant macromer, a crosslinker and a free radical catalyst and irradiating with UV light; wetting agents BAUSCH & LOMB INCORPORATED (US) 1992-08-04 US disclosed
WO-1992009639-A2 SURFACE-ACTIVE MACROMONOMERS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO disclosed
WO-1992009644-A1 SURFACE MODIFICATION OF POLYMER OBJECTS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO disclosed
WO-1992009650-A1 SURFACE COATING OF POLYMER OBJECTS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO disclosed
WO-1992009421-A2 MOLD MATERIALS FOR SILICONE CONTAINING LENS MATERIALS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO disclosed