Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | MC5R | P33032 | 1/20 | 0.37 |
| ▸ | MC3R | P41968 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588036 | 0.88 | CCR6 (0.57) | CCR6PAX8ANPEPDPP8DPP7 | |
| SCHEMBL8496673 | 0.86 | CCR6 (0.43) | CCR6PAX8ANPEPDPP8DPP7 | |
| SCHEMBL8588048 | 0.84 | CCR6 (0.45) | CCR6PAX8ANPEPDPP8DPP7 | |
| SCHEMBL413897 | 0.80 | CCR6 (0.53) | CCR6PAX8SLC1A3SLC1A1HTT | |
| SCHEMBL418498 | 0.77 | CCR6 (0.53) | CCR6PAX8 | |
| SCHEMBL18560009 | 0.77 | ANPEP (0.61) | CCR6PAX8ANPEPDPP8DPP7 | |
| SCHEMBL8492258 | 0.76 | MAPT (0.42) | CCR6PAX8 | |
| SCHEMBL8496670 | 0.76 | CCR6 (0.54) | CCR6PAX8ANPEPDPP8DPP7 | |
| SCHEMBL8498134 | 0.76 | CCR6 (0.48) | CCR6PAX8ANPEPDPP8DPP7 | |
| SCHEMBL7945013 | 0.76 | ANPEP (0.59) | CCR6PAX8ANPEPDPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050418-A1 | CATIONIC AMPHIPHILES CONTAINING LINKERS DERIVED FROM NEUTRAL OR POSITIVELY CHARGED AMINO ACIDS | GENZYME CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |