SCHEMBL8588284

SCHEMBL8588284

CSCC[C@H](NC(=O)c1ccc(C#Cc2cncnc2)cc1-c1ccccc1C)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 15/20 1.00
FNTB P49356 15/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8588279 1.00 FNTA (1.00) FNTAFNTB
SCHEMBL7916358 0.99 FNTA (0.98) FNTAFNTB
SCHEMBL7916362 0.99 FNTA (0.98) FNTAFNTB
SCHEMBL6771835 0.91 FNTA (1.00) FNTAFNTB
SCHEMBL6771842 0.91 FNTA (1.00) FNTAFNTB
Lithium Ion SCHEMBL7916361 0.91 FNTA (0.84) FNTAFNTB
SCHEMBL8591024 0.84 FNTA (1.00) FNTAFNTB
SCHEMBL7916491 0.83 FNTA (0.98) FNTAFNTB
SCHEMBL7916505 0.83 FNTA (0.98) FNTAFNTB
SCHEMBL7916501 0.83 FNTA (0.98) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998050030-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1998-11-12 WO claimed