Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL859124 | 0.94 | PIK3CA (0.36) | PIK3CAKIT | |
| SCHEMBL858635 | 0.92 | PIK3CA (0.35) | PIK3CAKIT | |
| SCHEMBL856544 | 0.90 | PIK3CA (0.34) | PIK3CAKIT | |
| SCHEMBL861157 | 0.90 | PIK3CA (0.34) | PIK3CAKIT | |
| SCHEMBL859086 | 0.89 | PIK3CA (0.36) | PIK3CAKIT | |
| SCHEMBL855872 | 0.89 | PIK3CA (0.36) | PIK3CAKIT | |
| SCHEMBL858913 | 0.89 | PIK3CA (0.36) | PIK3CAKIT | |
| SCHEMBL858898 | 0.87 | PIK3CA (0.37) | PIK3CAKIT | |
| SCHEMBL859718 | 0.86 | PIK3CA (0.35) | PIK3CAKIT | |
| SCHEMBL859568 | 0.86 | PIK3CA (0.39) | PIK3CAKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432779-A1 | BENZOXAZEPINES BASED P13K/MT0R INHIBITORS AGAINST PROLIFERATIVE DISEASES | Exelixis, Inc. (US) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010135524-A1 | BENZOXAZEPINES BASED P13K/MT0R INHIBITORS AGAINST PROLIFERATIVE DISEASES | EXELIXIS, INC. (US) | 2010-11-25 | — | — | WO | disclosed |