Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 12/20 | 0.59 |
| ▸ | FNTA | P49354 | 1/20 | 0.54 |
| ▸ | FNTB | P49356 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887273 | 1.00 | HRAS (0.59) | HRASFNTAFNTBLTA4HMME | |
| SCHEMBL6888473 | 0.97 | HRAS (0.57) | HRASFNTAFNTB | |
| SCHEMBL8590786 | 0.91 | HRAS (0.55) | HRASFNTAFNTBLTA4HMME | |
| SCHEMBL6891481 | 0.91 | HRAS (0.55) | HRASFNTAFNTBLTA4HMME | |
| SCHEMBL6888486 | 0.88 | HRAS (0.72) | HRASFNTAFNTBLTA4HMME | |
| SCHEMBL6888575 | 0.87 | HRAS (0.64) | HRASFNTAFNTBLTA4HMME | |
| SCHEMBL6888618 | 0.86 | HRAS (0.73) | HRASFNTAFNTBLTA4HMME | |
| SCHEMBL6887268 | 0.83 | HRAS (0.73) | HRASFNTAFNTBLTA4HMME | |
| SCHEMBL8590531 | 0.83 | HRAS (0.63) | HRASFNTAFNTBLTA4HMME | |
| SCHEMBL6888472 | 0.82 | HRAS (0.73) | HRASFNTAFNTBLTA4HMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998046625-A1 | DIPEPTIDE INHIBITORS OF PROTEIN FARNESYLTRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1998-10-22 | — | — | WO | claimed |